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Date Published: 24/03/2025
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DOI: 10.52714/dthu.14.04S.2025.1597
Issue
Vol. 14 No. 04S (2025): Special Issue of Mekong Delta Natural Science Conference
Section
Mekong Delta Natural Science Conference
How to Cite
Ho, T. B. N., Lam, V. K., & Ton, N. L. H. (2025). INVESTIGATION OF α -Glucosidase INHIBITORY POTENTIAL FOR DIABETES TREATMENT AND DEVELOPMENT OF FILTER TEA BAGS FROM MAI VANG LEAVES. Dong Thap University Journal of Science, 14(04S), 343-352. https://doi.org/10.52714/dthu.14.04S.2025.1597

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INVESTIGATION OF α -Glucosidase INHIBITORY POTENTIAL FOR DIABETES TREATMENT AND DEVELOPMENT OF FILTER TEA BAGS FROM MAI VANG LEAVES

Thi Bao Ngoc Ho1, Van Ky Lam1, Nu Lien Huong Ton2,
1 Medicinal Chemistry student, Course 48, College of Natural Sciences, Can Tho University, Vietnam
2 Can Tho University, Vietnam

Main Article Content

Abstract

From fresh leaves of Mai vang (Ochna integerrima (Lour.) Merr.), collected in Dong Thap province, the processing process has been completed to create tea bags with a weight of 2 g/pack. First, the materials are selected, washed, then roasted and stored in a filter bag according to the net weight of 2 g/package. On the other hand, the tea of the filter bag is infused with boiling water at 100°C to obtain the extract, which was then freeze-dried to yield an aqueous extract used for activity evaluation.. Water overhead survey of Mai vang leaf tea showed very good α-glucosidase inhibitory activity with an IC50 of 65.46±1.27 μg/mL, while the value of the acarbose control sample was 134.50 μg/mL under the same test conditions. These results confirm the inhibitory potential and therapeutic applicability of Mai vang leaves in the treatment of diabetes.

Keywords

α-glucosidase, Mai vang, Ochna integerrima, tea bag, diabetes inhibition.

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