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Date Published: 15/10/2015
Online Published: 15/10/2015
Abstract Views: 41
Views PDF: 46
DOI: https://doi.org/10.52714/dthu.15.8.2015.251
Issue
No. 15 (2015): Part B - Natural Sciences
Section
Natural Sciences Issue (Vietnamese)
How to Cite
Nguyen, A. T. (2015). New factor of obesity: endotoxin from gut microbiota. Dong Thap University Journal of Science, 15, 83-85. https://doi.org/10.52714/dthu.15.8.2015.251

New factor of obesity: endotoxin from gut microbiota

Anh Thoai Nguyen

Main Article Content

Abstract

Obesity is a multi-factor disease and is one of the world’s most common diseases. Recent studies have come up with the new causes of obesity. They are charaterized by a low-grade inflammation with the initial factor of endotoxin (Lipopolysaccharide - LPS) from the outer membrane of negative-Gram gut bacteria. The amount of these bacteria will increase with a high-fat diet, and thus, the percentage of LPS in blood also increases. Thereby, it accelerates obesity.

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Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Keywords

obesity, endotoxin, LPS, gut bacteria

References

[1]. A. P. Boroni Moreira, T. Fiche Salles Teixeira, M. do C. Gouveia Peluzio and R. de Cássia Gonçalves Alfenas (2012), "Gut microbiota and the development of obesity", Nutr Hosp., (5), p. 1408-1414.
[2]. P. D. Cani, J. Amar, M. A. Iglesias, M. Poggi, C. Knauf, D. Bastelica, et al. (2007), "Meta- bolic endotoxemia initiates obesity and insulin resistance", Diabetes, 56(7), p. 1761-1772.
[3]. M. Caroff and D. Karibian (2003), "Structure of bacterial lipopolysaccharides", Carbohydr Res, 338 (23), p. 2431-2447.
[4]. N. M. Delzenne, P. D. Cani (2008), "Implication de la flore intestinale dans le métabolisme énergétique", Medecine sciences, (24), p. 505-510.
[5]. K. Harris, A. Kassis, G. Major, and C. J. Chou (2012), "Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?", Journal of Obesity, 2012 (24), p. 1 - 14.
[6]. I. Ginsburg (2002), "Role of lipoteichoic acid in infection and inflammation", Lancet Infect Dis, 2 (3), p. 171-179.
[7]. R. E. Ley, F. Bckhed, P. Turnbaugh, C. A. Lozupone, R. D. Knight, and J. I. Gordon (2005), "Obesity alters gut microbial ecology", Proc Natl Acad Sci U S A., 102 (31), p. 11070-11075.
[8]. I. Moreno-Indias, F. Cardona, F. J. Tinahones and M. I. Queipo-Ortuđo (2014), "Impact of the gut microbiota on the development of obesity and type 2 diabetes mellitus", Evolutionary and Genomic Microbiology, (5), p. 190.
[9]. Nguyễn Anh Thoại, Phan Thế Đồng, Jaques Grober, (2013), "Tác động của nội độc tố li- popolysaccharide (LPS) đến sự chuyển hóa đường huyết", Tạp chí Dinh dưỡng và Thực phẩm, 9 (3), tr. 51- 59.
[10]. WHO (http://www.who.int/mediacentre/factsheets/fs311/en/).