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Date Published: 20/05/2025
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DOI: 10.52714/dthu.14.02S.2025.1717
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Vol. 14 No. 02S (2025): Special Issue in Natural Science
Section
Special Issue for Postgraduate
How to Cite
Nguyen, T. N. T., & Nguyen Thi, N. H. (2025). Application of Box–Behnken designs (BBD) in the synthesis of drug carriers - nano silica. Dong Thap University Journal of Science, 14(02S), 58-69. https://doi.org/10.52714/dthu.14.02S.2025.1717

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Application of Box–Behnken designs (BBD) in the synthesis of drug carriers - nano silica

Thi Ngoc Tram Nguyen1, , Ngoc Huyen Nguyen Thi2
1 Tra Vinh University, Tra Vinh province, Vietnam
2 School of Pharmacy, College of Medicine and Pharmacy, Tra Vinh University, Vietnam

Main Article Content

Abstract

Nowadays, the use of nanoparticles as "carriers" to deliver drugs to the correct location has attracted the attention of scientists. In particular, particle size is a critical factor affecting nanoparticles' ability to carry and release drugs. In this study, silica nanoparticles were synthesized by the Stober method combined with Box–Behnken designs (BBD). The resulting silica nanoparticles have sizes consistent with the predicted values, demonstrating the reliability of the proposed model. The study contributes to the development of promising materials for drug delivery systems.

Keywords

Box–Behnken designs, drug carrier, nano silica, nanomaterials, response surface methodology, SSN

Article Details

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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