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Date Published: 14/12/2024
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DOI: https://doi.org/10.52714/dthu.14.2.2025.1434
Issue
Vol. 14 No. 2 (2025): Natural Sciences Issue (Vietnamese)
Section
Natural Sciences Issue (Vietnamese)
How to Cite
Le, T. B., Le, T. T. X., Tran, C. L., Nguyen Thi Thuy, T., Tang Huynh, C., Le, T. D. T., Tran, N. P., Tran, P. X. M., Ho Tuong, A., Bui Thanh, L., & Nguyen, N. M. T. (2024). Study on chemical composition and bioactivities of Blumea balsamifera (L.) DC. Dong Thap University Journal of Science, 14(2), 31-39. https://doi.org/10.52714/dthu.14.2.2025.1434

Study on chemical composition and bioactivities of Blumea balsamifera (L.) DC.

Thi Bach Le1, , Thi Thanh Xuan Le2, Chi Linh Tran3, Tam Nguyen Thi Thuy1, Chi Tang Huynh1, Thi Diem Thuy Le1, Ngoc Phung Tran1, Pham Xuan Mai Tran1, Anh Ho Tuong1, Long Bui Thanh1, Ngoc Minh Thi Nguyen1
1 Department of Chemistry, College of Natural Sciences, Can Tho University, Vietnam
2 Faculty of Natural Sciences Teacher Education, School of Education, Dong Thap University, Cao Lanh 870000, Vietnam
3 Faculty of Medicine, Nam Can Tho University, Vietnam

Main Article Content

Abstract

This study aimed to evaluate the antioxidant and antibacterial activities of crude ethanol, n-hexane, and ethyl acetate extracts from Blumea balsamifera (L.) DC. Antioxidant capacity was assessed using DPPH and ABTS radical scavenging assays, while antibacterial activity was determined via the agar well diffusion method. The ethyl acetate extract demonstrated significant antioxidant activity, with IC50 values of 96.45 µg/mL and 58.36 µg/mL for DPPH and ABTS assays, respectively. The highest antibacterial activity was observed against Aeromonas caviae, where the ethyl acetate extract produced the largest inhibition zone (25.76±0.26 mm) at a concentration of 128 µg/mL. Chemical analysis of the leaves and stems from the ethyl acetate extract of Blumea balsamifera (L.) DC led to the identification of three compounds: luteolin  (1), (+)-catechin (2), and  oleanolic acid (3), confirmed by NMR spectroscopy and comparison with existing literature. These findings suggest that Blumea balsamifera is a promising medicinal plant with good biological activities.

Keywords

antioxidant activity, antibacterial activity, Blumea balsamifera (L.) DC., chemical composition

Article Details

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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